Ontology highlight
ABSTRACT:
SUBMITTER: Whitten MM
PROVIDER: S-EPMC4810840 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Whitten Miranda M A MM Facey Paul D PD Del Sol Ricardo R Fernández-Martínez Lorena T LT Evans Meirwyn C MC Mitchell Jacob J JJ Bodger Owen G OG Dyson Paul J PJ
Proceedings. Biological sciences 20160201 1825
RNA interference (RNAi) methods for insects are often limited by problems with double-stranded (ds) RNA delivery, which restricts reverse genetics studies and the development of RNAi-based biocides. We therefore delegated to insect symbiotic bacteria the task of: (i) constitutive dsRNA synthesis and (ii) trauma-free delivery. RNaseIII-deficient, dsRNA-expressing bacterial strains were created from the symbionts of two very diverse pest species: a long-lived blood-sucking bug, Rhodnius prolixus, ...[more]