An Overview of the Diagnosis and Management of Eosinophilic Esophagitis.

ABSTRACT: Eosinophilic esophagitis (EoE) is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa. The diagnosis requires esophageal biopsies demonstrating at least 15 eosinophils per high-powered field following a course of high-dose proton pump inhibitors. Management of EoE consists of the three Ds: drugs, dietary therapy, and esophageal dilation. In this review, we discuss the epidemiology, pathogenesis, diagnosis, and treatment of EoE to include the role of emerging therapies.

SUBMITTER: Singla MB 

PROVIDER: S-EPMC4822098 | biostudies-other | 2016

REPOSITORIES: biostudies-other