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In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer.


ABSTRACT: Metastatic breast cancer remains an incurable disease. Most patients experience objective treatment responses associated with palliation of symptoms; however, progression inevitably occurs. Thus, there is an urgent need for innovative therapeutic strategies that may halt disease progression. Adoptive T-cell therapy is a potent and promising treatment option with the potential to harness the intrinsic antitumor power of the immune system and provide long-term immunity against cancer.

SUBMITTER: Thakur A 

PROVIDER: S-EPMC4839366 | biostudies-other | 2016 Mar

REPOSITORIES: biostudies-other

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