Ontology highlight
ABSTRACT:
SUBMITTER: Ondeck MG
PROVIDER: S-EPMC4844086 | biostudies-other | 2016 Feb
REPOSITORIES: biostudies-other
Ondeck Matthew G MG Engler Adam J AJ
Journal of biomechanical engineering 20160201 2
Hyaluronic acid (HA) is a commonly used natural polymer for cell scaffolding. Modification by methacrylate allows it to be polymerized by free radicals via addition of an initiator, e.g., light-sensitive Irgacure, to form a methacrylated hyaluronic acid (MeHA) hydrogel. Light-activated crosslinking can be used to control the degree of polymerization, and sequential polymerization steps allow cells plated onto or in the hydrogel to initially feel a soft and then a stiff matrix. Here, the elastic ...[more]