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Involvement of USP24 in the DNA damage response.


ABSTRACT: Deubiquitination has emerged as an important mechanism of regulating DNA repair pathways. We recently reported that USP24 is a novel p53 deubiquitinase that stabilizes p53 upon DNA damage. USP24 is upregulated by DNA damaging agents and plays an important role in maintaining genome stability.

SUBMITTER: Zhang L 

PROVIDER: S-EPMC4845166 | biostudies-other | 2016 Jan

REPOSITORIES: biostudies-other

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