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A butterfly effect in cancer.


ABSTRACT: A point mutation in PIK3CA, the gene encoding the α isoform of class I phosphatidylinositol 3-kinase, induces extensive remodeling of the transcriptome and proteome, resulting in a gene signature that specifically resembles that of the basal subtype, but not other types, of breast cancer.

SUBMITTER: Vogt PK 

PROVIDER: S-EPMC4845179 | biostudies-other | 2016 Jan

REPOSITORIES: biostudies-other

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