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A single flexible RNAPII-CTD integrates many different transcriptional programs.


ABSTRACT: The RNAPII-CTD functions as a binding platform for coordinating the recruitment of transcription associated factors. Altering CTD function results in gene expression defects, although mounting evidence suggests that these effects likely vary among species and loci. Here we highlight emerging evidence of species- and loci-specific functions for the RNAPII-CTD.

SUBMITTER: Aristizabal MJ 

PROVIDER: S-EPMC4853039 | biostudies-other | 2016 Mar

REPOSITORIES: biostudies-other

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