Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Acevedo M
PROVIDER: S-EPMC4877815 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Gynecologic oncology research and practice 20140930
<h4>Background</h4>To explore the activity of dasatinib alone and in combination with gemcitabine and docetaxel in uterine leiomyosarcoma (uLMS) cell lines, and determine if dasatinib inhibits the SRC pathway.<h4>Methods</h4>SK-UT-1 and SK-UT-1B uLMS cells were treated with gemcitabine, docetaxel and dasatinib individually and in combination. SRC and paxcillin protein expression were determined pre- and post-dasatinib treatment using Meso Scale Discovery (MSD) multi-array immunogenicity assay. D ...[more]