Updates on drug discovery in ovarian cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Gibson SJ
PROVIDER: S-EPMC4878024 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Publications
Updates on drug discovery in ovarian cancer.
Gibson Steven J SJ Tewari Krishnansu S KS Monk Bradley J BJ Chase Dana M DM
Gynecologic oncology research and practice 20140930
Drug discovery in the ovarian cancer arena continues to launch important new clinical trials. Many biologic agents are being studied in phase II and phase III clinical trials for recurrent disease. These agents include compounds that disrupt angiogenesis through a variety of mechanisms. Other oncogenic pathways are also specifically targeted such as PARP, MEK, and topoisomerase inhibitors which are currently being studied in phase III trials. Various cytotoxic agents, as well as therapeutic vacc ...[more]
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