Ontology highlight
ABSTRACT:
SUBMITTER: Richardson J
PROVIDER: S-EPMC4893160 | biostudies-other | 2016 May
REPOSITORIES: biostudies-other
Richardson Jo J Gauert Anton A Briones Montecinos Luis L Fanlo Lucía L Alhashem Zainalabdeen Mohmammed ZM Assar Rodrigo R Marti Elisa E Kabla Alexandre A Härtel Steffen S Linker Claudia C
Cell reports 20160519 9
Collective cell migration is fundamental for life and a hallmark of cancer. Neural crest (NC) cells migrate collectively, but the mechanisms governing this process remain controversial. Previous analyses in Xenopus indicate that cranial NC (CNC) cells are a homogeneous population relying on cell-cell interactions for directional migration, while chick embryo analyses suggest a heterogeneous population with leader cells instructing directionality. Our data in chick and zebrafish embryos show that ...[more]