Targeting the sumoylation pathway in cancer stem cells.
Ontology highlight
ABSTRACT: Cancer stem cells (CSCs) represent a subset of tumor cells with tumor-initiating potential. We recently demonstrated that inhibition of the sumoylation pathway cleared the CSC population and repressed the outgrowth of basal breast cancer xenografts. Targeting the sumoylation pathway offers a novel treatment strategy for basal breast cancer.
SUBMITTER: Bogachek MV
PROVIDER: S-EPMC4905063 | biostudies-other | 2014 Jul-Sep
REPOSITORIES: biostudies-other
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