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The programmed cell death GLuc PCA library - a powerful tool for pathway discovery and drug screening.


ABSTRACT: A programmed cell death library based on the Gaussia luciferase protein-fragment complementation assay (GLuc PCA) enables detection of protein-protein interactions (PPI) within the cell death network and quantitative assessments of these interactions. Among future applications for the GLuc PCA cell death library is its potential use as a platform for PPI-targeted drug screening.

SUBMITTER: Gilad Y 

PROVIDER: S-EPMC4905220 | biostudies-other | 2014 Oct-Dec

REPOSITORIES: biostudies-other

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