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KiT: a MATLAB package for kinetochore tracking.

ABSTRACT: During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revealed many surprising facets of their behaviour. Here, we present 'KiT' (Kinetochore Tracking)-an easy-to-use, open-source software package for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D and multi-colour movies, quantification of fluorescence, integrated deconvolution, parallel execution and multiple algorithms for particle localization.KiT is free, open-source software implemented in MATLAB and runs on all MATLAB supported platforms. KiT can be downloaded as a package from http://www.mechanochemistry.org/mcainsh/software.php The source repository is available at https://bitbucket.org/jarmond/kit and under continuing development.Supplementary data are available at Bioinformatics online.jonathan.armond@warwick.ac.uk.

SUBMITTER: Armond JW

PROVIDER: S-EPMC4908324 | biostudies-other | 2016 Jun

REPOSITORIES: biostudies-other

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KiT: a MATLAB package for kinetochore tracking.

Armond Jonathan W JW Vladimirou Elina E McAinsh Andrew D AD Burroughs Nigel J NJ

Bioinformatics (Oxford, England) 20160215 12

<h4>Unlabelled</h4>During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revealed many surprising facets of their behaviour. Here, we present 'KiT' (Kinetochore Tracking)-an easy-to-use, open-source software package for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D and multi-colour movi ...[more]

PMID: 27153705

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Dataset Information

KiT: a MATLAB package for kinetochore tracking.

Publications

KiT: a MATLAB package for kinetochore tracking.

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