Clinical trials: past, current, and future for atypical Parkinsonian syndromes.
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ABSTRACT:
SUBMITTER: Tsai RM
PROVIDER: S-EPMC4920046 | biostudies-other | 2014 Apr
REPOSITORIES: biostudies-other
Publications
Clinical trials: past, current, and future for atypical Parkinsonian syndromes.
Tsai Richard M RM Boxer Adam L AL
Seminars in neurology 20140401 2
There are currently no effective Food and Drug Administration-approved treatments for atypical parkinsonian disorders such as progressive supranuclear palsy, corticobasal degeneration, dementia with Lewy bodies, or multiple system atrophy. Previous treatment trials for these disorders were focused on symptomatic support and did not affect disease progression. Recent breakthroughs in neuropathology and pathophysiology have allowed a new understanding of these disorders and investigation into pote ...[more]
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