Diversification of the Wnt gene family on the ancestral lineage of vertebrates.
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ABSTRACT:
SUBMITTER: Sidow A
PROVIDER: S-EPMC49236 | biostudies-other | 1992 Jun
REPOSITORIES: biostudies-other
Publications
Diversification of the Wnt gene family on the ancestral lineage of vertebrates.
Proceedings of the National Academy of Sciences of the United States of America 19920601 11
Diversification of the Wnt genes, a family of powerful developmental regulator molecules, is inferred by molecular evolutionary analyses. Fifty-five recently determined partial sequences from a variety of vertebrates and invertebrates, together with 17 published sequences, mostly from the mouse and Drosophila melanogaster, are analyzed. Wnt-1 through -7 originated before the last common ancestor of arthropods and deuterostomes lived. Another round of gene duplication, involving Wnt-3, -5, -7, an ...[more]
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