Ontology highlight
ABSTRACT:
SUBMITTER: Khera R
PROVIDER: S-EPMC4925508 | biostudies-other | 2016 Jun
REPOSITORIES: biostudies-other
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 20150517 Suppl 1
Plasmablastic lymphoma (PBL) is a rare aggressive neoplasm characterized by diffuse proliferation of large neoplastic cells with plasma cell immunophenotype. Cell of origin of PBL is believed to be a postgerminal center B-lymphocyte or plasmablast. The malignant cells in PBL usually do not express CD20 (B cell marker) but do express markers of plasmacytic differentiation, such as CD38, CD138, or MUM1/IRF4, akin to plasma cell myeloma (PCM). PBL though originally described in the oral cavity, has ...[more]