Cerebral white matter structure is associated with DSM-5 schizophrenia symptom dimensions.
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ABSTRACT:
SUBMITTER: Viher PV
PROVIDER: S-EPMC4925890 | biostudies-other | 2016
REPOSITORIES: biostudies-other
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Cerebral white matter structure is associated with DSM-5 schizophrenia symptom dimensions.
Viher Petra V PV Stegmayer Katharina K Giezendanner Stéphanie S Federspiel Andrea A Bohlhalter Stephan S Vanbellingen Tim T Wiest Roland R Strik Werner W Walther Sebastian S
NeuroImage. Clinical 20160616
Diffusion tensor imaging (DTI) studies have provided evidence of widespread white matter (WM) abnormalities in schizophrenia. Although these abnormalities appear clinically significant, the relationship to specific clinical symptoms is limited and heterogeneous. This study examined the association between WM microstructure and the severity of the five main DSM-5 schizophrenia symptom dimensions. DTI was measured in forty patients with schizophrenia spectrum disorders. Using Tract-Based Spatial S ...[more]
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