Ontology highlight
ABSTRACT:
SUBMITTER: Pitzer VE
PROVIDER: S-EPMC4938081 | biostudies-other | 2016 Jun
REPOSITORIES: biostudies-other
Pitzer Virginia E VE Aguas Ricardo R Riley Steven S Loeffen Willie L A WL Wood James L N JL Grenfell Bryan T BT
Journal of the Royal Society, Interface 20160601 119
Pigs have long been hypothesized to play a central role in the emergence of novel human influenza A virus (IAV) strains, by serving as mixing vessels for mammalian and avian variants. However, the key issue of viral persistence in swine populations at different scales is ill understood. We address this gap using epidemiological models calibrated against seroprevalence data from Dutch finishing pigs to estimate the 'critical herd size' (CHS) for IAV persistence. We then examine the viral phylogen ...[more]