Ontology highlight
ABSTRACT:
SUBMITTER: Auslander N
PROVIDER: S-EPMC4942812 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Auslander Noam N Yizhak Keren K Weinstock Adam A Budhu Anuradha A Tang Wei W Wang Xin Wei XW Ambs Stefan S Ruppin Eytan E
Scientific reports 20160713
Disrupted regulation of cellular processes is considered one of the hallmarks of cancer. We analyze metabolomic and transcriptomic profiles jointly collected from breast cancer and hepatocellular carcinoma patients to explore the associations between the expression of metabolic enzymes and the levels of the metabolites participating in the reactions they catalyze. Surprisingly, both breast cancer and hepatocellular tumors exhibit an increase in their gene-metabolites associations compared to non ...[more]