Towards Consensus Gene Ages.
Ontology highlight
ABSTRACT:
SUBMITTER: Liebeskind BJ
PROVIDER: S-EPMC4943184 | biostudies-other | 2016 Jun
REPOSITORIES: biostudies-other
Publications
Towards Consensus Gene Ages.
Liebeskind Benjamin J BJ McWhite Claire D CD Marcotte Edward M EM
Genome biology and evolution 20160627 6
Correctly estimating the age of a gene or gene family is important for a variety of fields, including molecular evolution, comparative genomics, and phylogenetics, and increasingly for systems biology and disease genetics. However, most studies use only a point estimate of a gene's age, neglecting the substantial uncertainty involved in this estimation. Here, we characterize this uncertainty by investigating the effect of algorithm choice on gene-age inference and calculate consensus gene ages w ...[more]
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