Ontology highlight
ABSTRACT:
SUBMITTER: Yamamoto Y
PROVIDER: S-EPMC4947697 | biostudies-other | 2016 Jul
REPOSITORIES: biostudies-other
Yamamoto Yoichiro Y Offord Chetan P CP Kimura Go G Kuribayashi Shigehiko S Takeda Hayato H Tsuchiya Shinichi S Shimojo Hisashi H Kanno Hiroyuki H Bozic Ivana I Nowak Martin A MA Bajzer Željko Ž Dingli David D
British journal of cancer 20160701 2
<h4>Background</h4>Interstitial brachytherapy for localised prostate cancer may be followed by transient increases in prostate-specific antigen (PSA) that resolve without therapy. Such PSA bounces may be associated with an improved outcome but often cause alarm in the patient and physician, and have defied explanation.<h4>Methods</h4>We developed a mathematical model to capture the interactions between the tumour, radiation and anti-tumour immune response. The model was fitted to data from a lar ...[more]