Ontology highlight
ABSTRACT:
SUBMITTER: Harrison E
PROVIDER: S-EPMC4964889 | biostudies-other | 2016 May-Jun
REPOSITORIES: biostudies-other
Harrison Ellie E Dytham Calvin C Hall James P J JP Guymer David D Spiers Andrew J AJ Paterson Steve S Brockhurst Michael A MA
Mobile genetic elements 20160504 3
Conjugative plasmids play a vital role in bacterial adaptation through horizontal gene transfer. Explaining how plasmids persist in host populations however is difficult, given the high costs often associated with plasmid carriage. Compensatory evolution to ameliorate this cost can rescue plasmids from extinction. In a recently published study we showed that compensatory evolution repeatedly targeted the same bacterial regulatory system, GacA/GacS, in populations of plasmid-carrying bacteria evo ...[more]