Ontology highlight
ABSTRACT:
SUBMITTER: Du YP
PROVIDER: S-EPMC4971512 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Du Yuan-Peng YP Chang Hsun-Hui HH Yang Sheng-Yu SY Huang Shing-Jong SJ Tsai Yu-Ju YJ Huang Joseph Jen-Tse JJ Chan Jerry Chun Chung JC
Scientific reports 20160803
Pif is a crucial protein for the formation of the nacreous layer in Pinctada fucata. Three non-acidic peptide fragments of the aragonite-binding domain (Pif80) are selected, which contain multiple copies of the repeat sequence DDRK, to study the interaction between non-acidic peptides and aragonite. The polypeptides DDRKDDRKGGK (Pif80-11) and DDRKDDRKGGKDDRKDDRKGGK (Pif80-22) have similar binding affinity to aragonite. Solid-state NMR data indicate that the backbones of Pif80-11 and Pif80-22 pep ...[more]