Ontology highlight
ABSTRACT:
SUBMITTER: Uezumi A
PROVIDER: S-EPMC4983081 | biostudies-other | 2016 Aug
REPOSITORIES: biostudies-other
Uezumi Akiyoshi A Nakatani Masashi M Ikemoto-Uezumi Madoka M Yamamoto Naoki N Morita Mitsuhiro M Yamaguchi Asami A Yamada Harumoto H Kasai Takehiro T Masuda Satoru S Narita Asako A Miyagoe-Suzuki Yuko Y Takeda Shin'ichi S Fukada So-Ichiro S Nishino Ichizo I Tsuchida Kunihiro K
Stem cell reports 20160801 2
Skeletal muscle contains two distinct stem/progenitor populations. One is the satellite cell, which acts as a muscle stem cell, and the other is the mesenchymal progenitor, which contributes to muscle pathogeneses such as fat infiltration and fibrosis. Detailed and accurate characterization of these progenitors in humans remains elusive. Here, we performed comprehensive cell-surface protein profiling of the two progenitor populations residing in human skeletal muscle and identified three previou ...[more]