Advances in glucose metabolism research in colorectal cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Fang S
PROVIDER: S-EPMC4998148 | biostudies-other | 2016 Sep
REPOSITORIES: biostudies-other
Publications
Advances in glucose metabolism research in colorectal cancer.
Biomedical reports 20160718 3
Cancer cells uptake glucose at a higher rate and produce lactic acid rather than metabolizing pyruvate through the tricarboxylic acid cycle. This adaptive metabolic shift is termed the Warburg effect. Recently progress had been made regarding the mechanistic understanding of glucose metabolism and associated diagnostic and therapeutic methods, which have been investigated in colorectal cancer. The majority of novel mechanisms involve important glucose metabolism associated genes and miRNA regula ...[more]
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