Targeting EGFR in lung cancer: Lessons learned and future perspectives.
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ABSTRACT:
SUBMITTER: Steuer CE
PROVIDER: S-EPMC5024712 | biostudies-other | 2015 Nov
REPOSITORIES: biostudies-other
Publications
Targeting EGFR in lung cancer: Lessons learned and future perspectives.
Steuer Conor E CE Ramalingam Suresh S SS
Molecular aspects of medicine 20150527
The development of individualized therapies has become the focus of current oncology research. Precision medicine has demonstrated great potential for bringing safe and effective drugs to those patients stricken with cancer, and is becoming a reality as more oncogenic drivers of malignancy are discovered. The discovery of Epidermal Growth Factor Receptor (EGFR) mutations as a driving mutation in non-small cell lung cancer (NSCLC) and the subsequent success of the tyrosine kinase inhibitors (TKI) ...[more]
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