Ontology highlight
ABSTRACT:
SUBMITTER: Stock AT
PROVIDER: S-EPMC5030799 | biostudies-other | 2016 Sep
REPOSITORIES: biostudies-other
The Journal of experimental medicine 20160905 10
Kawasaki disease (KD) is the leading cause of pediatric heart disease in developed countries. KD patients develop cardiac inflammation, characterized by an early infiltrate of neutrophils and monocytes that precipitates coronary arteritis. Although the early inflammatory processes are linked to cardiac pathology, the factors that regulate cardiac inflammation and immune cell recruitment to the heart remain obscure. In this study, using a mouse model of KD (induced by a cell wall Candida albicans ...[more]