Ontology highlight
ABSTRACT:
SUBMITTER: Namgung B
PROVIDER: S-EPMC5038815 | biostudies-other | 2016 Sep
REPOSITORIES: biostudies-other
Sensors (Basel, Switzerland) 20160921 9
In this study, a biomimetic microfluidic plasma separation device is discussed. The design of the device drew inspiration from in vivo observations of enhanced cell-free layer (CFL) formation downstream of vascular bifurcations. The working principle for the plasma separation was based on the plasma skimming effect in an arteriolar bifurcation, which is modulated by CFL formation. The enhancement of the CFL width was achieved by a local hematocrit reduction near the collection channel by creatin ...[more]