Ascaris hemoglobin gene: plant-like structure reflects the ancestral globin gene.
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ABSTRACT:
SUBMITTER: Sherman DR
PROVIDER: S-EPMC50623 | biostudies-other | 1992 Dec
REPOSITORIES: biostudies-other
Publications
Ascaris hemoglobin gene: plant-like structure reflects the ancestral globin gene.
Sherman D R DR Kloek A P AP Krishnan B R BR Guinn B B Goldberg D E DE
Proceedings of the National Academy of Sciences of the United States of America 19921201 24
Animal globin genes have two introns at strictly conserved positions, while plant globin genes have both of these as well as an additional, central intron. It has been proposed that a common ancestor gene had three introns, one of which was subsequently lost from animal but not plant globin genes. We have elucidated the cDNA sequence and gene structure of a hemoglobin from the parasitic nematode Ascaris suum and found a plant-like central intron, providing strong evidence for a three-intron ance ...[more]
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