Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Mut JV
PROVIDER: S-EPMC5068885 | biostudies-other | 2016 Jan
REPOSITORIES: biostudies-other
Sanchez-Mut J V JV Heyn H H Vidal E E Moran S S Sayols S S Delgado-Morales R R Schultz M D MD Ansoleaga B B Garcia-Esparcia P P Pons-Espinal M M de Lagran M M MM Dopazo J J Rabano A A Avila J J Dierssen M M Lott I I Ferrer I I Ecker J R JR Esteller M M
Translational psychiatry 20160119
Different neurodegenerative disorders often show similar lesions, such as the presence of amyloid plaques, TAU-neurotangles and synuclein inclusions. The genetically inherited forms are rare, so we wondered whether shared epigenetic aberrations, such as those affecting DNA methylation, might also exist. The studied samples were gray matter samples from the prefrontal cortex of control and neurodegenerative disease-associated cases. We performed the DNA methylation analyses of Alzheimer's disease ...[more]