Ontology highlight
ABSTRACT:
SUBMITTER: Screaton GR
PROVIDER: S-EPMC50718 | biostudies-other | 1992 Dec
REPOSITORIES: biostudies-other
Screaton G R GR Bell M V MV Jackson D G DG Cornelis F B FB Gerth U U Bell J I JI
Proceedings of the National Academy of Sciences of the United States of America 19921201 24
The CD44 molecule is known to display extensive size heterogeneity, which has been attributed both to alternative splicing and to differential glycosylation within the extracellular domain. Although the presence of several alternative exons has been partly inferred from cDNA sequencing, the precise intron-exon organization of the CD44 gene has not been described to date to our knowledge. In the present study we describe the structure of the human CD44 gene, which contains at least 19 exons spann ...[more]