Ontology highlight
ABSTRACT:
SUBMITTER: Larsen E
PROVIDER: S-EPMC5075177 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Larsen Eric E Menashe Idan I Ziats Mark N MN Pereanu Wayne W Packer Alan A Banerjee-Basu Sharmila S
Molecular autism 20161021
<h4>Background</h4>The search for genetic factors underlying autism spectrum disorders (ASD) has led to the identification of hundreds of genes containing thousands of variants that differ in mode of inheritance, effect size, frequency, and function. A major challenge involves assessing the collective evidence in an unbiased, systematic manner for their functional relevance.<h4>Methods</h4>Here, we describe a scoring algorithm for prioritization of candidate genes based on the cumulative strengt ...[more]