Ontology highlight
ABSTRACT:
SUBMITTER: Bruekers SM
PROVIDER: S-EPMC5079382 | biostudies-other | 2016 Sep
REPOSITORIES: biostudies-other
Bruekers Stéphanie M C SM Jaspers Maarten M Hendriks José M A JM Kurniawan Nicholas A NA Koenderink Gijsje H GH Kouwer Paul H J PH Rowan Alan E AE T S Huck Wilhelm W
Cell adhesion & migration 20160224 5
The mechanical and structural properties of the extracellular matrix (ECM) play an important role in regulating cell fate. The natural ECM has a complex fibrillar structure and shows nonlinear mechanical properties, which are both difficult to mimic synthetically. Therefore, systematically testing the influence of ECM properties on cellular behavior is very challenging. In this work we show two different approaches to tune the fibrillar structure and mechanical properties of fibrin hydrogels. Ad ...[more]