MiR-155: A Novel Target in Allergic Asthma.
Ontology highlight
ABSTRACT:
SUBMITTER: Zhou H
PROVIDER: S-EPMC5085797 | biostudies-other | 2016 Oct
REPOSITORIES: biostudies-other
Publications
miR-155: A Novel Target in Allergic Asthma.
Zhou Hong H Li Junyao J Gao Peng P Wang Qi Q Zhang Jie J
International journal of molecular sciences 20161024 10
MicroRNAs (miRNAs), a class of small non-coding RNAs of 18-24 nucleotides in length, function to posttranscriptionally regulate protein expression. miR-155 was one of the first identified and, to date, the most studied miRNA, and has been linked to various cellular processes such as modulation of immune responses and oncogenesis. Previous studies have identified miR-155 as a crucial positive regulator of Th1 immune response in autoimmune diseases, but as a suppressor of Th2 immunity in allergic ...[more]
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