Ontology highlight
ABSTRACT:
SUBMITTER: Takayama Y
PROVIDER: S-EPMC5128866 | biostudies-other | 2016 Nov
REPOSITORIES: biostudies-other
Takayama Yuko Y Shirai Masaki M Masuda Fumie F
Scientific reports 20161130
Histone gene expression is regulated in a cell cycle-dependent manner, with a peak at S phase, which is crucial for cell division and genome integrity. However, the detailed mechanisms by which expression of histone genes are tightly regulated remain largely unknown. Fission yeast Ams2, a GATA-type zinc finger motif-containing factor, is required for activation of S phase-specific core histone gene transcription. Here we report the molecular characterisation of Ams2. We show that the zinc finger ...[more]