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Mature CD8+ T-cell clonal expansion in the oral cavity and digestive tract: a severe lymphoid malignancy that mimics Crohn's disease.


ABSTRACT: In patients with atypical Crohn's disease features, including severe oral ulcerations and resistance to standard treatment, the possibility of a mature clonal CD8+ T-cell lymphoproliferative disorder should be investigated. Clinicians should be aware of this differential diagnosis because CD8+ T-cell lymphoma prognosis can be remarkably favorable upon oral treatment with cyclophosphamide.

SUBMITTER: Coppo P 

PROVIDER: S-EPMC5134143 | biostudies-other | 2016 Dec

REPOSITORIES: biostudies-other

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