Ontology highlight
ABSTRACT:
SUBMITTER: Olonisakin TF
PROVIDER: S-EPMC5142085 | biostudies-other | 2016 Dec
REPOSITORIES: biostudies-other
Olonisakin Tolani F TF Li Huihua H Xiong Zeyu Z Kochman Elizabeth J K EJ Yu Minting M Qu Yanyan Y Hulver Mei M Kolls Jay K JK St Croix Claudette C Doi Yohei Y Nguyen Minh-Hong MH Shanks Robert M Q RM Mallampalli Rama K RK Kagan Valerian E VE Ray Anuradha A Silverstein Roy L RL Ray Prabir P Lee Janet S JS
The Journal of infectious diseases 20160928 12
Klebsiella pneumoniae remains an important cause of intrapulmonary infection and invasive disease worldwide. K. pneumoniae can evade serum killing and phagocytosis primarily through the expression of a polysaccharide capsule, but its pathogenicity is also influenced by host factors. We examined whether CD36, a scavenger receptor that recognizes pathogen and modified self ligands, is a host determinant of K. pneumoniae pathogenicity. Despite differences in serum sensitivity and virulence of 3 dis ...[more]