Differential stimulation of the retina with subretinally injected exogenous neurotransmitter: A biomimetic alternative to electrical stimulation.
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ABSTRACT:
SUBMITTER: Rountree CM
PROVIDER: S-EPMC5144088 | biostudies-other | 2016 Dec
REPOSITORIES: biostudies-other
Publications
Differential stimulation of the retina with subretinally injected exogenous neurotransmitter: A biomimetic alternative to electrical stimulation.
Rountree Corey M CM Inayat Samsoon S Troy John B JB Saggere Laxman L
Scientific reports 20161208
Subretinal stimulation of the retina with neurotransmitters, the normal means of conveying visual information, is a potentially better alternative to electrical stimulation widely used in current retinal prostheses for treating blindness from photoreceptor degenerative diseases. Yet, no subretinal electrical or chemical stimulation study has stimulated the OFF and ON pathways differentially through inner retinal activation. Here, we demonstrate the feasibility of differentially stimulating retin ...[more]
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2011-11-21 | E-GEOD-26174 | biostudies-arrayexpress