Ontology highlight
ABSTRACT:
SUBMITTER: Feld JJ
PROVIDER: S-EPMC5216450 | biostudies-other | 2017 Jan
REPOSITORIES: biostudies-other
Feld Jordan J JJ Jacobson Ira M IM Sulkowski Mark S MS Poordad Fred F Tatsch Fernando F Pawlotsky Jean-Michel JM
Liver international : official journal of the International Association for the Study of the Liver 20160929 1
Over the past two decades, ribavirin has been an integral component of treatment for hepatitis C virus (HCV) infection, where it has been shown to improve the efficacy of (pegylated) interferon. However, because of treatment-limiting side effects and its additive toxicity with interferon, the search for interferon- and ribavirin-free regimens has been underway. The recent approvals of all-oral direct acting antivirals (DAAs) have revolutionized the HCV therapeutic landscape, and initially it was ...[more]