Ontology highlight
ABSTRACT:
SUBMITTER: Karadimou G
PROVIDER: S-EPMC5220676 | biostudies-other | 2017 Jan
REPOSITORIES: biostudies-other
Karadimou Glykeria G Folkersen Lasse L Berg Martin M Perisic Ljubica L Discacciati Andrea A Roy Joy J Hansson Göran K GK Persson Jonas J Paulsson-Berne Gabrielle G
Cardiovascular research 20161115 1
<h4>Aims</h4>Processes in the development of atherosclerotic lesions can lead to plaque rupture or erosion, which can in turn elicit myocardial infarction or ischaemic stroke. The aims of this study were to determine whether Toll-like receptor 7 (TLR7) gene expression levels influence patient outcome and to explore the mechanisms linked to TLR7 expression in atherosclerosis.<h4>Methods and results</h4>Atherosclerotic plaques were removed by carotid endarterectomy (CEA) and subjected to gene arra ...[more]