Cold sensitivity of thermophilic and mesophilic RNA polymerases.
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ABSTRACT:
SUBMITTER: Kulbachinskiy A
PROVIDER: S-EPMC524896 | biostudies-other | 2004 Nov
REPOSITORIES: biostudies-other
Publications
Cold sensitivity of thermophilic and mesophilic RNA polymerases.
Kulbachinskiy A A Bass I I Bogdanova E E Goldfarb A A Nikiforov V V
Journal of bacteriology 20041101 22
RNA polymerase from mesophilic Deinococcus radiodurans displays the same cold sensitivity of promoter opening as RNA polymerase from the closely related thermophilic Thermus aquaticus. This suggests that, contrary to the accepted view, cold sensitivity of promoter opening by thermophilic RNA polymerases may not be a consequence of their thermostability. ...[more]
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