Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth.
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ABSTRACT:
SUBMITTER: Hussain A
PROVIDER: S-EPMC5301302 | biostudies-other | 2017
REPOSITORIES: biostudies-other
Publications
Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth.
Hussain A A Suleiman M S MS George S J SJ Loubani M M Morice A A
The open cardiovascular medicine journal 20170124
Hypoxic Pulmonary vasoconstriction (HPV) describes the physiological adaptive process of lungs to preserves systemic oxygenation. It has clinical implications in the development of pulmonary hypertension which impacts on outcomes of patients undergoing cardiothoracic surgery. This review examines both acute and chronic hypoxic vasoconstriction focusing on the distinct clinical implications and highlights the role of calcium and mitochondria in acute <i>versus</i> the role of reactive oxygen spec ...[more]
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