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Automatic MRI segmentation of para-pharyngeal fat pads using interactive visual feature space analysis for classification.


ABSTRACT: BACKGROUND:Obstructive sleep apnea (OSA) is a public health problem. Detailed analysis of the para-pharyngeal fat pads can help us to understand the pathogenesis of OSA and may mediate the intervention of this sleeping disorder. A reliable and automatic para-pharyngeal fat pads segmentation technique plays a vital role in investigating larger data bases to identify the anatomic risk factors for the OSA. METHODS:Our research aims to develop a context-based automatic segmentation algorithm to delineate the fat pads from magnetic resonance images in a population-based study. Our segmentation pipeline involves texture analysis, connected component analysis, object-based image analysis, and supervised classification using an interactive visual analysis tool to segregate fat pads from other structures automatically. RESULTS:We developed a fully automatic segmentation technique that does not need any user interaction to extract fat pads. Our algorithm is fast enough that we can apply it to population-based epidemiological studies that provide a large amount of data. We evaluated our approach qualitatively on thirty datasets and quantitatively against the ground truths of ten datasets resulting in an average of approximately 78% detected volume fraction and a 79% Dice coefficient, which is within the range of the inter-observer variation of manual segmentation results. CONCLUSION:The suggested method produces sufficiently accurate results and has potential to be applied for the study of large data to understand the pathogenesis of the OSA syndrome.

SUBMITTER: Shahid ML 

PROVIDER: S-EPMC5309996 | biostudies-other | 2017 Feb

REPOSITORIES: biostudies-other

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Automatic MRI segmentation of para-pharyngeal fat pads using interactive visual feature space analysis for classification.

Shahid Muhammad Laiq Ur Rahman ML   Chitiboi Teodora T   Ivanovska Tetyana T   Molchanov Vladimir V   Völzke Henry H   Linsen Lars L  

BMC medical imaging 20170214 1


<h4>Background</h4>Obstructive sleep apnea (OSA) is a public health problem. Detailed analysis of the para-pharyngeal fat pads can help us to understand the pathogenesis of OSA and may mediate the intervention of this sleeping disorder. A reliable and automatic para-pharyngeal fat pads segmentation technique plays a vital role in investigating larger data bases to identify the anatomic risk factors for the OSA.<h4>Methods</h4>Our research aims to develop a context-based automatic segmentation al  ...[more]

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