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Understanding the role of serotonin in psychiatric diseases.


ABSTRACT: Serotonin (5-HT) continues to attract researchers' interest after almost a century. However, despite these efforts, its role has not yet been fully elucidated. It is now evident that 5-HT does not modulate single functions but rather a multiplicity of activities and behaviors present in both normal and several pathological conditions in a less deterministic way than previously assumed. This article aims to briefly review some of the latest advancements in the general role of 5-HT in psychiatry, particularly in depression, and offer the author's personal reflections.

SUBMITTER: Marazziti D 

PROVIDER: S-EPMC5325064 | biostudies-other | 2017

REPOSITORIES: biostudies-other

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Understanding the role of serotonin in psychiatric diseases.

Marazziti Donatella D  

F1000Research 20170223


Serotonin (5-HT) continues to attract researchers' interest after almost a century. However, despite these efforts, its role has not yet been fully elucidated. It is now evident that 5-HT does not modulate single functions but rather a multiplicity of activities and behaviors present in both normal and several pathological conditions in a less deterministic way than previously assumed. This article aims to briefly review some of the latest advancements in the general role of 5-HT in psychiatry,  ...[more]

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