Ontology highlight
ABSTRACT:
SUBMITTER: Saez CG
PROVIDER: S-EPMC53431 | biostudies-other | 1990 Feb
REPOSITORIES: biostudies-other
Saez C G CG Myers J C JC Shows T B TB Leinwand L A LA
Proceedings of the National Academy of Sciences of the United States of America 19900201 3
Myosin is a ubiquitous eukaryotic contractile protein that generates the force responsible for such diverse cellular movements as muscle contraction and cytokinesis. Although there have been numerous studies of sarcomeric myosin heavy chain (MHC) genes, no molecular clones have been reported that encode mammalian nonmuscle MHC. This study presents the molecular genetic characterization of a human nonmuscle MHC that is expressed in fibroblasts, endothelial cells, and macrophages. Human nonmuscle ...[more]