The role of Notch signalling in ovarian angiogenesis.
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ABSTRACT:
SUBMITTER: Xie Q
PROVIDER: S-EPMC5346233 | biostudies-other | 2017 Mar
REPOSITORIES: biostudies-other
Publications
The role of Notch signalling in ovarian angiogenesis.
Xie Qi Q Cheng Zuowang Z Chen Xiaocui X Lobe Corrinne G CG Liu Ju J
Journal of ovarian research 20170311 1
In adults, the ovary is characterized with extensive angiogenesis and regular intervals of rapid growth. Ovarian function is dependent on the network of angiogenic vessels which enable the follicle and/or corpus luteum to receive oxygen, nutrients and hormonal support. Abnormal angiogenesis is involved in the induction and development of pathological ovary, such as polycystic ovary syndrome and ovarian cancer. Notch signalling pathway is one of the primary regulators of angiogenesis and a therap ...[more]
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