Prognostic role of cyclin B1 in solid tumors: a meta-analysis.
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ABSTRACT:
SUBMITTER: Ye C
PROVIDER: S-EPMC5356794 | biostudies-other | 2017 Jan
REPOSITORIES: biostudies-other
Publications
Prognostic role of cyclin B1 in solid tumors: a meta-analysis.
Ye Chenyang C Wang Ji J Wu Pin P Li Xiaofen X Chai Ying Y
Oncotarget 20170101 2
Cyclin B1 is a key mitotic cyclin in the G2-M phase transition of the cell cycle and is overexpressed in various malignant tumors. Numerous studies have reported contradictory evidences of the correlation between cyclin B1 expression and prognosis in human solid tumors. To address this discrepancy, we conducted a meta-analysis with 17 published studies searched from PubMed and Medline. Cyclin B1 overexpression was significantly associated with poor 3-year overall survival (OS) (OR = 2.05, 95% CI ...[more]
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