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High-voltage VIM Region Deep Brain Stimulation Mimicking Progressive Supranuclear Palsy.


ABSTRACT: Deep brain stimulation (DBS) for essential tremor (ET) can cause unwanted side effects.A patient with ET underwent unilateral dual-lead thalamic DBS. He later developed parkinsonism with atypical features and was diagnosed with progressive supranuclear palsy. During presentation for a second opinion, stimulation-induced side effects were suspected. Inactivation of DBS resolved atypical features and superimposed idiopathic Parkinson disease (PD) was diagnosed.This case illustrates the importance of recognizing the possible influence of stimulation-induced side effects and discusses when to utilize dual-lead DBS for ET and the co-occurrence of ET and PD.

SUBMITTER: Patterson A 

PROVIDER: S-EPMC5374517 | biostudies-other | 2017

REPOSITORIES: biostudies-other

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High-voltage VIM Region Deep Brain Stimulation Mimicking Progressive Supranuclear Palsy.

Patterson Addie A   Okun Michael S MS   Hess Christopher C  

Tremor and other hyperkinetic movements (New York, N.Y.) 20170320


<h4>Background</h4>Deep brain stimulation (DBS) for essential tremor (ET) can cause unwanted side effects.<h4>Case report</h4>A patient with ET underwent unilateral dual-lead thalamic DBS. He later developed parkinsonism with atypical features and was diagnosed with progressive supranuclear palsy. During presentation for a second opinion, stimulation-induced side effects were suspected. Inactivation of DBS resolved atypical features and superimposed idiopathic Parkinson disease (PD) was diagnose  ...[more]

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