Ontology highlight
ABSTRACT:
SUBMITTER: Dorsey MJ
PROVIDER: S-EPMC5385855 | biostudies-other | 2017 Mar
REPOSITORIES: biostudies-other
Dorsey Morna J MJ Dvorak Christopher C CC Cowan Morton J MJ Puck Jennifer M JM
The Journal of allergy and clinical immunology 20170301 3
Severe combined immunodeficiency (SCID) is characterized by severely impaired T-cell development and is fatal without treatment. Newborn screening (NBS) for SCID permits identification of affected infants before development of opportunistic infections and other complications. Substantial variation exists between treatment centers with regard to pretransplantation care, and transplantation protocols for NBS identified infants with SCID, as well as infants with other T-lymphopenic disorders detect ...[more]