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DistributedFBA.jl: high-level, high-performance flux balance analysis in Julia.

ABSTRACT: Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl.ronan.mt.fleming@gmail.com.Supplementary data are available at Bioinformatics online.

SUBMITTER: Heirendt L

PROVIDER: S-EPMC5408791 | biostudies-other | 2017 May

REPOSITORIES: biostudies-other

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DistributedFBA.jl: high-level, high-performance flux balance analysis in Julia.

Heirendt Laurent L Thiele Ines I Fleming Ronan M T RMT

Bioinformatics (Oxford, England) 20170501 9

<h4>Motivation</h4>Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.<h4>Results</h4>DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions o ...[more]

PMID: 28453682

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